2012 Fiscal Year Final Research Report
Effect of imatinib in bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation
Project/Area Number |
23790901
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Respiratory organ internal medicine
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Research Institution | Kanazawa University |
Principal Investigator |
WASEDA Yuko 金沢大学, 医学系, 助教 (80536037)
|
Project Period (FY) |
2011 – 2012
|
Keywords | 閉塞性細気管支炎 |
Research Abstract |
In the mouse lung transplantation model, BO was significantly controlled when we used the c-kit knockout model as donor. We had the possibility to be able to reduce BO, which is the biggest complications after the lung transplantation, by controlling c-kit of the donor. Therefore, We thought about the possibility that we could decrease BO with imatinib.
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