Development of a dose calculation method and a treatment planning system for radiotherapy based on the Boltzmann transport equation

2013 Fiscal Year Final Research Report

• Project/Area Number: 23791449
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Juntendo University
• Principal Investigator: SUGIMOTO Satoru 順天堂大学, 医学(系)研究科(研究院), 助教 (00373316)
• Project Period (FY): 2011 – 2013
• Keywords: 放射線治療 / 線量計算 / 線量分布最適化 / 線量不確かさ / 小照射野 / モンテカルロ計算 / ボルツマン方程式 / 動体追尾照射

Research Abstract

The purpose of the project was to develop a fast and accurate dose calculation code for the state-of-the-art radiotherapy of cancer and a treatment planning optimization system based on it. While we could not complete the development of the dose calculation code, we revealed the necessary conditions which should be satisfied by the new dose calculation code by investigating small fields, where the uncertainty of usual dose calculation methods can be large. As for the optimization for treatment planning, we developed the method of the evaluation of dose uncertainty, which is necessary for the minimization of dose uncertainty. We also developed the dose calculation method for moving tumors, which can be used for the optimization considering tumor motions.

Research Products

• [Journal Article] The dosimetric impact of respiratory breast movement and daily setup error on tangential whole breast irradiation using conventional wedge, field-in-field and irregular surface compensator techniques (2013)
  • Author(s): Tomohisa Furuya, Satoru Sugimoto, Chie Kurokawa, Shuichi Ozawa, Kumiko Karasawa, Keisuke Sasai
  • Journal Title: Journal of Radiation Research Volume: Vol. 54 Pages: pp. 157-165
  • DOI: 10.1093/jrr/rrs064
  • Peer Reviewed
• [Journal Article] Comparison of total MU and segment areas in VMAT and step-and-shoot IMRT plans (2013)
  • Author(s): Motohiro Kawashima, Shuichi Ozawa, Akihiro Haga, Akira Sakumi, Chie Kurokawa, Satoru Sugimoto, Kumiko Karasawa, Keiichi Nakagawa, Keisuke Sasai
  • Journal Title: Radiological Physics and Technology Volume: Vol. 6 Pages: pp. 14-20
  • DOI: 10.1007/s12194-012-0164-3
  • Peer Reviewed
• [Presentation] 治療計画システムPLanUNC上でのVero 4DRTのコミッショニングの検討 (2013)
  • Author(s): 杉本聡、井上達也、馬場竜太、荻原義貞、徳山克一、江部和勇
  • Organizer: 第106回日本医学物理学会学術大会
  • Place of Presentation: 大阪大学コンベンションセンター
  • Year and Date: 20130900
• [Presentation] Evaluation of inherent dose-uncertainty for VMAT using a dose uncertainty model (2013)
  • Author(s): Tatsuya Inoue, Satoru Sugimoto, Yataro Horikawa, Chie Kurokawa, Kyohei Fukata, Akira Isobe, Kana Ito, Keisuke Sasai
  • Organizer: 2013 AAPM Annual Meeting
  • Place of Presentation: Indianapolis, Indiana, USA
  • Year and Date: 20130800
• [Presentation] 小照射野における検出器応答の検出部分体積・材質依存性のモンテカルロ計算による評価 (2012)
  • Author(s): 杉本聡、深田恭平、井上達也、黒河千恵、笹井啓資
  • Organizer: 第104回日本医学物理学会学術大会
  • Place of Presentation: つくば国際会議場
  • Year and Date: 20120900
• [Presentation] Study of restricted mass stopping power ratio in small electron tube fields (2012)
  • Author(s): Satoru Sugimoto, Shuichi Ozawa, Hiromasa Takatou, Katsuichi Tokuyama, Hirotaka Maruyama, Takahiro Yamagishi, Ryuta Baba, Kazuyu Ebe, Keisuke Sasai
  • Organizer: 2012 AAPM Annual Meeting
  • Place of Presentation: Charlotte, North Carolina, USA
  • Year and Date: 20120700
• [Presentation] モンテカルロ線量計算の高速化に向けたHadoopによる分散環境の実践効果 (2012)
  • Author(s): 市村友寛、杉本聡、深田恭平、小澤修一、唐澤久美子、笹井啓資
  • Organizer: 第103回日本医学物理学会学術大会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 20120400
• [Presentation] Monte Carlo calculation of mean electron energies in small circular electron fields at 45 degree incident angle (2011)
  • Author(s): Satoru Sugimoto, Shuichi Ozawa, Hiromasa Takatou, Katsuichi Tokuyama, Hirotaka Maruyama, Takahiro Yamagishi, Ryuta Baba, Kazuyu Ebe
  • Organizer: the 6th Japan-Korea Joint Meeting on Medical Physics and the 11th Asia-Oceania Congress of Medical Physics
  • Place of Presentation: Fukuoka
  • Year and Date: 20110900