2012 Fiscal Year Final Research Report

Study of mechanism of a rapid and profound transition in glucose concentration during the Pringle maneuver

Research Project

Project/Area Number	23791709
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Anesthesiology/Resuscitation studies
Research Institution	Kochi University
Principal Investigator	FUKUNAGA Kayo 高知大学, 教育研究部医療学系, 助教 (00571035)
Project Period (FY)	2011 – 2012
Keywords	肝虚血再潅流 / 人工膵臓
Research Abstract	The Pringle maneuver is performed in hepatectomy due to reduce hemorrhage. Our previous study using a continuous blood glucose monitoring revealed that liver ischemia/reperfusion causes a rapid and profound transition in glucose concentration. Our study showed that glucose release from the hepatic vein and sinusoid leads to a rapid elevation in systemic blood glucose levels after liver ischemia/reperfusion. Furthermore, we investigated whether iatrogenic blood glucose variation cause inflammation.

(1 results)