Creation of fish scale collagen material technology integrated with material engineering and cell biology

2014 Fiscal Year Final Research Report

• Project/Area Number: 24241044
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Nanomaterials/Nanobioscience
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: IKOMA Toshiyuki 東京工業大学, 理工学研究科, 准教授 (20370306)
• Co-Investigator(Kenkyū-buntansha): TANAKA Junzo 東京工業大学, 大学院理工学研究科, 教授 (10343831) ; TANAKA Toshiaki 東京工業大学, 大学院生命理工学研究科, 助教 (40263446) ; YOSHIOKA Tomohiko 東京工業大学, 大学院理工学研究科, 助教 (50452016)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: ナノ機能材料

Outline of Final Research Achievements

The aim of this project is to construct the hierarchical structure of fish scale including collagen fibrils. The collagen extracted from fish scale was fibrogenesis under the flow field controlled temperature, pH and salt concentrations, and the alignment of collagen fibrils were formed. Furthermore, in situ technology about the observation of collagen production process inside cells were established. To construct the hierarchical structure similar to scale by fish cells, the substrate morphology was of great importance.

Free Research Field

生体材料