Synthetic study of new functional compounds based on the novel rare metal-free coupling methods

2016 Fiscal Year Final Research Report

• Project/Area Number: 24249001
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Chemical pharmacy
• Research Institution: Ritsumeikan University
• Principal Investigator: Kita Yasuyuki 立命館大学, 総合科学技術研究機構, 教授 (00028862)
• Co-Investigator(Kenkyū-buntansha): 土肥 寿文 立命館大学, 薬学部, 准教授 (50423116) ; 藤岡 弘道 大阪大学, 薬学研究科(研究院), 教授 (10173410)
• Project Period (FY): 2012-04-01 – 2017-03-31
• Keywords: 有機化学

Outline of Final Research Achievements

We have developed new environmentally-friendly reactions and reagents for reducing the use of rare metals, and applied them as the sustainable methods for the synthesis of useful compounds. By performing the synthetic researches of natural products and their analogues, and functional molecules, the new metal catalyst-free oxidative coupling reactions using hypervalent iodine reagent, in combination withour synthetic methods utilizing the unique reactivities of iodine, sulfur, and oxygen (oxonium), have become the useful methods for advances of drug development study and material chemistry.

Free Research Field

合成化学