Effect of exercise training on sarcopenia: focused on fiber number

2014 Fiscal Year Final Research Report

• Project/Area Number: 24500796
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Sports science
• Research Institution: Tohoku Institute of Technology
• Principal Investigator: MASATAKA Suwa 東北工業大学, 公私立大学の部局等, 准教授 (50464392)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: サルコペニア / 筋線維数 / 老化 / 運動

Outline of Final Research Achievements

The purpose of this research was to investigate the effect of exercise training or resveratrol treatment on age-related muscle fiber loss in mice. The research demonstrated that mice aged 24 months showed significant decrease in muscle fiber number of plantaris muscle in comparison to the mice aged 3 months. Wheel running training during 3 to 24 months age significantly attenuated such decrease. On the other hand, functional overload by tenotomy of gastrocnemius tendon or resveratrol treatment did not induce such phenomenon. The results imply that long-term endurance training would attenuate the age-related fiber loss in fast-twitch muscle.

Free Research Field

運動生理学