2015 Fiscal Year Final Research Report
Studies on the cross-talk among organs of anti-inflammatory effects by cereal intake and exploratory research of active components
Project/Area Number |
24500995
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits, studies on eating habits
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Research Institution | Otsuma Women's University |
Principal Investigator |
AOE Seiichiro 大妻女子大学, 家政学部, 教授 (90365049)
|
Project Period (FY) |
2012-04-01 – 2016-03-31
|
Keywords | メタボリックシンドローム / 大麦 / β-グルカン / 雑穀 / 肥満モデルマウス |
Outline of Final Research Achievements |
Anti-inflammatory effects of barley beta-glucan intake on inflammation of liver, skin tissues as well as adipose tissues by modification of gut microbiota were studied. Compositions of brown rice, black rice, rye, oat were also analyzed and compared to the barley. These results indicated that parameters related to metabolic syndrome were deteriorated in the high fat diet by cross talk among dysbiosis, production of short chain fatty acid synthesis, large bowel and organs inflammation. Our results also indicated that high beta-glucan barley has protective effect on inflammation of organs by modification of gut microbiota compared to other cereals.
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Free Research Field |
生活科学
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