2014 Fiscal Year Final Research Report
Functional analysis of cell cycle-associated microRNAs
| Project/Area Number |
24570201
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Molecular biology
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| Research Institution | Meiji University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | マイクロＲＮＡ |
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| Outline of Final Research Achievements |
MicroRNA (miRNA) has been shown to be involved in regulation of the etiology of serious illness such as cancer and metabolic diseases. It is estimated that human cells have approximately more than 1,000 kinds of miRNAs. In this study, we focused on five miRNAs that could be associated with cell cycle regulation and aimed to reveal functional aspects including target gene identification and epigenetic regulation of miRNAs. It is expected that the results obtained from this study would be useful not only for diagnosis of cancer but also for epigenetic therapy and for promotion of microRNA-based medicine.
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| Free Research Field |
細胞生物学
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