2014 Fiscal Year Final Research Report
Analysis of genetic diversity of the extended MHC region of Japanese quail
| Project/Area Number |
24580431
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Basic veterinary science/Basic zootechnical science
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| Research Institution | Tokyo University of Agriculture |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HARA Hiromi 東京農業大学, 農学部, 助教 (00343567)
SHIINA Takashi 東海大学, 医学部, 准教授 (00317744)
HOSOMICHI Kazuyoshi 金沢大学, 医学部, 准教授 (50420948)
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| Research Collaborator |
MAEDA Yoshimi
MIZUTANI Makoto
MANNEN Hideyuki
MILLER Marcia
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Keywords | ウズラ / MHC / TRIM / CD1 / DNA多型 / ハプロタイプ / 連鎖 / 組換え |
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| Outline of Final Research Achievements |
1. TRIM sub-region and CD1 sub-region were identified in major histocompatibility complex from Japanese quail (Extended MhcCoja region).
2. The making of the polymorphism catalogue (1) The design of the high-density DNA polymorphism marker: We built the following thirteen markers, four markers in TRIM subregion, three markers in MHC class IIB subregion, four markers in MHC class I subregion, and two markers in CD1 subregion. (2) Haplotype analysis: The genes in each subregion have linkage each other, but there was recombination region between each subregion. (3) The gene structure of each haplotype: We suggested the differences among haplotypes of the number of functional MHC class IIB loci.
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| Free Research Field |
動物分子免疫学
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