2015 Fiscal Year Final Research Report
Nano vectors with biosurfactant MEL-A
| Project/Area Number |
24590060
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Hiromitsu 愛知学院大学, 薬学部, 教授 (30275094)
INHO Yoshikazu 愛知学院大学, 薬学部, 講師 (90434547)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | nano vectors / liposome / biosurfactant / gene transfection / medical treatment / membrane fusion |
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| Outline of Final Research Achievements |
The liposomes made by biosurfactant(MEL-A) dramatically increased the efficiency in transfection of plasmid DNAs and foreign DNAs. The efficiency by nano vector is derived from the unique pathway similar to that by certain RNA virus vectors. From the safety and low toxicity the nano vector would appear to be a new operating technique with great potential in gene transfection and drug delivery in medical treatment.
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| Free Research Field |
生物物理学
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