2014 Fiscal Year Final Research Report
Clinical comparison of nuclear reactor BNCT and accelerator BNCT for head and neck cancer.
| Project/Area Number |
24592611
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Otorhinolaryngology
|
|---|
| Research Institution | University of Tsukuba (2013-2014)
Kawasaki Medical School (2012) |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
HIRATSUKA Jyunichi 川崎医科大学, 医学部, 教授 (30192298)
OHNISHI Kayoko 筑波大学, 医学医療系, 講師 (60529832)
|
|---|
| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | BNCT / 進行頭頸部癌 / 再発頭頸部癌 / 機能温存 / 有害事象 |
|---|
| Outline of Final Research Achievements |
BNCT is effective in head and neck cancer. However, widespread skin invasion and recurrence after irradiation are risk factors for CBS after BNCT. Careful attention should be paid to the occurrence of CBS if the tumor is located adjacent to the carotid artery. The presence of skin invasion of recurrent lesions after irradiation at CBS onset is an ominous sign of lethal consequences. We must be aware of these signs to perform BNCT safely. This protocol for BNCT in recurrent and advanced head and neck cancer is promising in terms of decreasing the incidence of fatal CBS.
|
| Free Research Field |
耳鼻咽喉科頭頸部外科学
|
