2014 Fiscal Year Final Research Report
Construction of cooperating peptide probes for tumor detection
| Project/Area Number |
24650649
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Clinical oncology
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| Research Institution | Japanese Foundation for Cancer Research |
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Principal Investigator |
MATSUMURA Sachiko 公益財団法人がん研究会, がん研究所, 特任研究員 (90414052)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
|
| Keywords | がん / ペプチド / リガンド / ナノバイオ |
|---|
| Outline of Final Research Achievements |
The aim of this work is to construct peptide probes that use a cooperative interaction of molecules containing ligands on cells. Peptides with a ligand sequence were assembled to form a nano-sized structure. The assemblage containing many ligand peptides specifically bound to tumor cells that expressed the target proteins.
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| Free Research Field |
生体関連化学、ナノバイオ
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