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2014 Fiscal Year Final Research Report

Establishing the basic study for unmyelinated and myelinated central nervous system

Research Project

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Project/Area Number 24659436
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Neurology
Research InstitutionThe Institute of Physical and Chemical Research

Principal Investigator

NUKINA Nobuyuki  独立行政法人理化学研究所, 脳科学総合研究センター, 客員主管研究員 (10134595)

Project Period (FY) 2012-04-01 – 2015-03-31
Keywords無髄線維 / 線条体投射線維 / sodium channel / beta4 subunit / Nav1.2
Outline of Final Research Achievements

The role of unmyelinated fiber in central nervous system is not well elucidated. Even which nervous system is unmylinated is well unknown. We recently found the striatal projection fibers are unmylinated suggested by the distribution pattern of sodium channel beta4 subunit. In this study we further confirm this fact and identified several features of those unmyelinated fibers(Miyazaki et al Nat Commun2014)

Free Research Field

病態脳科学

URL: 

Published: 2016-06-03  

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