Role of enteric bacteria on adaptation to low protein diet

2016 Fiscal Year Final Research Report

• Project/Area Number: 24687032
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Physical anthropology
• Research Institution: Jikei University School of Medicine
• Principal Investigator: Iwase Tadayuki 東京慈恵会医科大学, 医学部, 講師 (80385294)
• Project Period (FY): 2012-04-01 – 2017-03-31
• Keywords: 細菌学 / 人類学 / 栄養学 / 進化・適応 / 腸内細菌

Outline of Final Research Achievements

We designed and developed an incubator for 15N-gas exposure experiments with a domestic manufacturer. Mice with or without nitrogen-fixing bacteria were kept for 3 days under 15N gas in the incubator. The internal organs (intestinal contents, intestinal tract, liver, body hair) of the mice were harvested and analyzed nitrogen Isotope ratio of the samples using an elemental analysis / isotope ratio mass spectrometer to measure. The results indicated that a statistically significant increase in the nitrogen isotope ratio was found in intestinal content, intestinal tract, and liver. In contrast, no significance was observed in the body hair.

Free Research Field

細菌学