2015 Fiscal Year Final Research Report
Development of new bond-forming reactions catalyzed by hypervalent species
| Project/Area Number |
24689002
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Keywords | 新規反応開発 |
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| Outline of Final Research Achievements |
In this research, we have developed novel bond-forming methods not usually occurring without the use of metal catalysts, by modifying the introduction of hypervalent iodine species and the reductive bond-forming processes of specific importance in reaction design of hypervalent iodine chemistry. In addition, a new design of the reagents and process development aiming at enhancing the reaction efficiencies have been carried out with success. Based on the newly developed strategy as well as our original synthetic techniques, by synthesizing a family of highly oxygenated and functionalized aromatics and their derivatives, we have further extended the strategy to a series of new constructing methods of molecular backbones for enabling the synthesis of core structures of bioactive compounds and functional materials.
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| Free Research Field |
有機合成化学
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