2013 Fiscal Year Final Research Report
The origin and evolution of mammalian sex determination; how is marsupial male determined?
| Project/Area Number |
24770225
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Evolutionary biology
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| Research Institution | The Graduate University for Advanced Studies (2013)
大学共同利用機関法人情報・システム研究機構(新領域融合研究センター及びライフサイ (2012) |
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Principal Investigator |
KATSURA Yukako 総合研究大学院大学, その他の研究科, 研究員 (00624727)
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| Project Period (FY) |
2012-04-01 – 2014-03-31
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| Keywords | 性決定 / 有袋類 |
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| Research Abstract |
To understand how marsupial male can be genetically determined, we have investigated molecular evolution and function of male determining gene SRY, and identified testis-expressed genes in marsupials by transcriptome analyses. Based on the molecular evolutionary and biochemical analyses, marsupial (wallabies, koalas and so on) SRY sequences are not conserved well compared to eutherian (humans, mice and so on) SRY, but the function of marsupial SRY is similar to eutherians. This study strongly suggests that marsupial male determining gene is also SRY.
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