2013 Fiscal Year Final Research Report
Mechanism of changes in energy metabolism by food components via TRP channels
| Project/Area Number |
24780131
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | The University of Shiga Prefecture |
|---|
Principal Investigator |
MORI Noriyuki 滋賀県立大学, 人間文化学部, 助手 (90585184)
|
|---|
| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | TRP channel / ally isothiocyanate / carbohydrate oxidation / mice |
|---|
| Research Abstract |
We investigated the relationship between the changes in glucose metabolism by ally isothiocyanate (AITC), which is an agonist of transient receptor potential (TRP) channel, and insulin secretion. AITC increased blood insulin levels and it mediated TRPV1. AITC could enhance an insulin secretion from isolated pancreatic islets. The sympathetic nerve system, mediating beta-adrenergic receptor, is involved in the increase in carbohydrate oxidation and the increase in the blood insulin levels.
|
Research Products
(6 results)
