Hepatic cancer stem cell derived cancer: radiologic pathologic correlation

2014 Fiscal Year Final Research Report

• Project/Area Number: 24791283
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kanazawa University
• Principal Investigator: KAZUO Kozaka 金沢大学, 医学系, 助教 (80547175)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Keywords: 混合型肝癌 / 細胆管細胞癌 / CT / MRI

Outline of Final Research Achievements

Liver stem cell-derived liver cancer is classifiable into a typical, mixed, cholangiolocellular subtypes. These diagnostics, prognosis and treatment is not determined.
In this retrospective study, though we couldn't determine the specific findings in typical and mixed type, we could reveal that cholangiolocellular subtype showed characteristic findings on dynamic CT/MRI and low accumulation of FDG compared with ordinaly cholangiocellular carcinoma. Furthermore there were different cancer gene expressions between cholangiolocellular subtype and intrahepatic cholangiocellular carcinoma. We believe that cholangiolocellular subtype is unique and it should be considered as a independent disease from ordinary cholangiocellular carcinoma.

Free Research Field

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