2013 Fiscal Year Final Research Report
Enhancement of functional expression of osteoblastic and periosteal cells by gingival fibroblasts with paracrine effect of fibroblastic growth factors
| Project/Area Number |
24792114
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Tokyo Dental College |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2014-03-31
|
| Keywords | 骨再生 / 線維芽細胞増殖因子 / 歯肉結合組織 / 細胞間相互作用 |
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| Research Abstract |
Gingival fibroblasts enhanced osteoblastic and periosteal proliferation and differentiation. The mechanism was involved in paracrine secretion of FGF-1 and -18 from GF and subsequent autocrine secresion of these growth factors from osteoblasts and periosteal cells.
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