2015 Fiscal Year Final Research Report
Study on the molecular mechanisms of baculovirus tissue tropism
| Project/Area Number |
25292196
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Insect science
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KATSUMA Susumu 東京大学, 農学生命科学研究科, 准教授 (20378863)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | バキュロウイルス / 組織トロピズム / 行動制御 / カイコ / 昆虫病理学 |
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| Outline of Final Research Achievements |
The Baculoviridae is a large family of pathogens that are infectious for arthropods, particularly insects of the Lepidoptera. Baculoviruses are known to potentially encode >100 proteins, some of which are utilized to control host physiology at cellular and/or organismal levels. Lepidopteran baculoviruses show distinct tissue tropism in host insect larvae, but the molecular mechanisms of this tropism and its relationship to viral control of host caterpillars are largely unknown. In this study, I attempted to identify the genes involved in baculovirus tissue tropism and to clarify their roles in baculoviral host control.
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| Free Research Field |
昆虫病理学
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