2015 Fiscal Year Final Research Report
Development of multi-peptide tumor vaccine for renal cell carcinoma
| Project/Area Number |
25293336
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kinki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
DEVELASCO Marco 近畿大学, 医学部, 助教 (20449838)
MINAMI Takafumi 近畿大学, 医学部, 講師 (70340809)
HARADA Mamoru 島根大学, 医学部, 教授 (50260716)
YOSHIMURA Kazuhiro 近畿大学, 医学部, 教授 (20283757)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 腎細胞癌 / 癌ワクチン / ペプチドワクチン / 免疫療法 |
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| Outline of Final Research Achievements |
We have been working on the development of new MHC-class-I restricted peptide vaccines for five independent therapeutic targets and have identified a significant candidate EPOR, PDL1 and HIF1. We made the application of patents for EPOR and PDL1 peptide vaccine and are preparing the application for HIF1. Together with CA9 and VEGFR1 previously developed peptide vaccines, we established multi-peptide vaccination system using these five peptide vaccines.
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| Free Research Field |
泌尿器腫瘍学
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