Highly selective inclusion of organic molecules using the phase transition of calixarene crystals

2015 Fiscal Year Final Research Report

• Project/Area Number: 25410032
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Organic chemistry
• Research Institution: Tohoku University
• Principal Investigator: Morohashi Naoya 東北大学, 工学(系)研究科(研究院), 准教授 (70344819)
• Co-Investigator(Renkei-kenkyūsha): HATTORI TETSUTARO 東北大学, 大学院工学研究科, 教授 (70241536)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: カリックスアレーン / チアカリックスアレーン / 包接 / 有機結晶 / アルコール / アミン / 芳香族異性体

Outline of Final Research Achievements

Crystals of calix[4]arene and thiacalix[4]arene exhibit distinct differences in inclusion properties towards primary alcohols, which originated from the difference in the crystal packing of inclusion crystals according to the property of bridging groups. Selective inclusion of methylamines and switching of guest selectivity by solvent polarity using crystals of thiacalix[4]arene are achieved. It is found that the property of crystals of calix[4]arene can be applied to selective inclusion of aromatic regioisomers. Furthermore, synthesis of linear carboxylic acid-type host molecule having a 2,2'-thiodiphenol structure and selective inclusion of amine isomers using it are succeeded.

Free Research Field

有機化学