2015 Fiscal Year Final Research Report
Analysis of the photoreceptive protein Opn5 found in invertebrates
| Project/Area Number |
25440167
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 光受容 / オプシン / シグナル伝達 |
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| Outline of Final Research Achievements |
Opn5 constitutes one of the photoreceptive protein, opsin, groups, whose gene is widely distributed in deuterostome genomes. We previously revealed that vertebrate Opn5 is classified into several subgroups and is diversified based on their molecular properties and tissue distribution patterns. In this study, we analyzed Opn5 found from deuterostomes other than vertebrates. We successfully obtained the recombinant proteins of these Opn5 proteins after reconstituted with 11-cis-retinal. The molecular properties of these Opn5 proteins shared with those of several vertebrate Opn5 subgroups. In addition, we detected Opn5 expression signals both during early development and in adult of sea urchin. These data suggest that sea urchin utilizes Opn5 in a variety of developmental stages to respond to light environment.
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| Free Research Field |
分子生理学
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