2015 Fiscal Year Final Research Report
Involvement of oxygen stress in exacerbation of asthma induced by polycyclic aromatic hydrocarbons
| Project/Area Number |
25460166
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental and hygienic pharmacy
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Hiroyuki 金沢大学, 医学系, 教授 (30231476)
HITOMI Yoshiaki 金沢大学, 医学系, 准教授 (70231545)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 多環芳香族炭化水素類 / 慢性咳嗽 / アレルギー疾患 / 咳 / 大気汚染 |
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| Outline of Final Research Achievements |
The effect of ambient dust (such as PM2.5) including long-range transboundary air pollution on health is a concern. In this study, it is shown that polycyclic aromatic hydrocarbons contained in ambient dust aggravated cough symptoms of adult chronic cough (bronchial asthma, cough variant asthma, atopic cough) patients. The effect of polycyclic aromatic hydrocarbons on cough symptoms of cough variant asthma patients and atopic cough patients are stronger than that of bronchial asthma patients. It is suggested that the effect of polycyclic aromatic hydrocarbons on cough symptoms is stronger in patients whose allergy symptoms are weak.
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| Free Research Field |
予防医学
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