2015 Fiscal Year Final Research Report
Immunohistochemical analysis of Thy-1 and PDGF in IgG4-related disease
| Project/Area Number |
25460465
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Human pathology
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
KUROSE Nozomu 金沢医科大学, 医学部, 助教 (10319048)
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| Co-Investigator(Kenkyū-buntansha) |
Minato Hiroshi 金沢医科大学, 医学部, 教授 (10293367)
MASAKI Yasufumi 金沢医科大学, 医学部, 教授 (40238895)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | IgG4関連疾患 / 線維化 |
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| Outline of Final Research Achievements |
To quantify the degree of fibrosis in various organs in IgG4 related disease, and to clarify the mechanism of the fibrosis in IgG4 related disease, this study was performed. Pericyte and myofibroblast cells were thought to be related to fibrosis of IgG4 related disease. Compared to non-IgG4 related disease, the degree of fibrosis was significantly higher. It was possible to quantify the degree of fibrosis in IgG4 related disease.
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| Free Research Field |
病理診断学
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