2015 Fiscal Year Final Research Report
microRNA released from adipose cells regulate vascular remodeling
| Project/Area Number |
25461131
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | The University of Tokushima |
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Principal Investigator |
YAGI Shusuke 徳島大学, 大学院医歯薬学研究部, 助教 (00507650)
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| Co-Investigator(Kenkyū-buntansha) |
SATA Masataka 徳島大学, 大学院医歯薬学研究部, 教授 (80345214)
ISHIDA Masayoshi 琉球大学, 医学(系)研究科(研究院), 助教 (50643251)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | マイクロRNA / 脂肪細胞 |
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| Outline of Final Research Achievements |
Perivascular fat produces various vasoactive substances and exerts important rolls in vascular chronic inflammation and vascular remodeling.It is known that microRNAs released from cells enter another cells to regulate gene expression. In this study, we showed that miR-100 released from adipose cells regulates mTOR in smooth muscle cells, indicating that miRNA regulates cell proliferation.
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| Free Research Field |
循環器内科
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