2015 Fiscal Year Final Research Report
Involvement of oxidative stress and check points in CKD-MBD
| Project/Area Number |
25461247
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Kidney internal medicine
|
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| Research Institution | The University of Tokushima |
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Principal Investigator |
HAMADA Yasuhiro 徳島大学, 大学院医歯薬学研究部, 教授 (30397830)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Keywords | 骨代謝 / 低回転骨 |
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| Outline of Final Research Achievements |
Diabetes Mellitus is one of the representative diseases to cause chronic kidney disease - mineral and bone disorder (CKD-MBD). The bone disorder of diabetes shows low turnover bone. In order to elucidate the involvement of oxidative stress in low turnover bone, statin, which is a lipid-lowering medication and has anti-oxidative effct, were administered to diabetic animal model. In conclusion, administration of statin improved low turnover diabetic osteopenia.
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| Free Research Field |
腎臓内科学
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