Oxygen-enhanced dynamic MR imaging of cerebral vessels and cerebrospinal fluid.

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461815
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: FUSHIMI Yasutaka 京都大学, 医学(系)研究科(研究院), 助教 (90639014)
• Co-Investigator(Renkei-kenkyūsha): OKADA Tomohisa 京都大学, 医学研究科, 准教授 (30321607) ; YAMAMOTO Akira 京都大学, 医学研究科, 助教 (60525567) ; KANAGAKI Mitsunori 京都大学, 医学研究科, 助教 (50378676) ; TOGASHI Kaori 京都大学, 医学研究科, 教授 (90135484)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: MRI / 酸素 / T1短縮効果 / 脳脊髄液 / 高空間分解能 / 高時間分解能

Outline of Final Research Achievements

T1 shortening effect due to oxygen inhalation was studied in order to develop oxygen-enhanced MR imaging for cerebral vessels and cerebrospinal fluid. Dynamic signal change in cerebrospinal fluid (CSF) space was demonstrated at 3 tesla MRI. The signal in the subarachnoid space was more rapidly and more strongly observed than that in the ventricles. Our results suggested the soluble oxygen might diffuse directly into CSF space without entering choroid plexus, however it has been originally thought that choroid plexus is the only organ which produce CSF.

Free Research Field

放射線医学