Development of screening examination and a therapy for vascular endothelial cells disorder preceding diabetic angiopathy

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461849
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Tokai University
• Principal Investigator: FUKUYAMA Naoto 東海大学, 医学部, 准教授 (50349338)
• Co-Investigator(Renkei-kenkyūsha): MORI Hidezo 東海大学, 医学部, 教授 (90146598) ; TAKIZAWA Shunya 東海大学, 医学部, 教授 (70197234)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: 動脈硬化 / 微小血管造影法 / 糖尿病

Outline of Final Research Achievements

The patients with diabetes increase rapidly in Japan. Diabetes causes arteriosclerotic disease such as myocardial infarction or cerebral infarction and becomes the main cause of death. However, the initial treatment that targeted arteriosclerosis is impossible because the detection of the arteriosclerotic early-stage disease due to diabetes is difficult.
In this study, we detected the vascular endothelial cells disorder that was arteriosclerotic early-stage disease by microangiography using the synchrotron radiation and showed that the early treatment could be provided.

Free Research Field

生理学、総合内科学、活性酸素学、高齢医学、放射線医学、栄養学、病態生理学