Fusion of US and PET/CT using Real-time virtual sonography for breast imaging

2015 Fiscal Year Final Research Report

• Project/Area Number: 25461852
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Aichi Medical University
• Principal Investigator: ANDO Takahito 愛知医科大学, 医学部, 助教 (40634134)
• Co-Investigator(Kenkyū-buntansha): NAKANO Shogo 愛知医科大学, 乳腺・内分泌外科, 教授 (20351108) ; FUJII Kimihito 愛知医科大学, 乳腺・内分泌外科, 准教授 (00524331) ; KOUSAKA Junko 愛知医科大学, 乳腺・内分泌外科, 助教 (50440748) ; ISHIGUCHI Tsuneo 愛知医科大学, 放射線科, 教授 (70115525)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: RVS / 超音波fusion技術 / 磁気ナビゲーション / PET/CT / Breast Cancer / Reccurrence

Outline of Final Research Achievements

PET/CT is more sensitive in detecting of recurrent disease of the breast. When incidental FDG uptake with high standard uptake value (SUV) is detected in loco-regional lesion by PET/CT, sonographic confirmation needs to be done immediately. The aim of this study was to evaluate the role of Real-time virtual sonography (RVS) in the management of sonographic localization of FDG activity. We performed PET/CT in 11 patients. Sonographic detection rate was determined for FDG uptake with or without RVS. Of the 11 patients, a total of 14 FDG uptake lesions were detected as loco-regional recurrence. Of these, 7 (50%) could be identified in targeted US without RVS, but 14 (100%) were identified in targeted US with RVS (p<0.05). The RVS was able to correctly project FDG uptake information onto a body surface, as we checked sonography form images without operator’s skill. Our results suggest that RVS can sonographically identify FDG uptake lesions with excellent accuracy.

Free Research Field

放射線科学