2015 Fiscal Year Final Research Report
Development of 3-D intestinal regeneration using the adipose tissue-derived mesenchymal stem cell
| Project/Area Number |
25462775
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | The University of Tokushima |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
YADA Keigo 徳島大学, 病院, 助教 (00633893)
UTSUNOMIYA Toru 徳島大学, 大学院医歯薬学研究部, 准教授 (30304801)
KURITA Nobuhiro 徳島大学, 病院, 特任教授 (30335814)
MORI Hiroki 大阪府立母子保健総合医療センター, 病院, 医長 (70448330)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 短腸症候群 / 腸管再生 / 脂肪由来幹細胞 |
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| Outline of Final Research Achievements |
The aim of this study was to investigate intestinal regeneration in a surgical model using the adipose tissue-derived mesenchymal stem cell. Roux-en-Y bypass procedures using a silicone tube and a Vicryl mesh tube were performed on Wistar rats. In 8 weeks after implantation with a silicone tube, the complete intestinal regeneration was recognized. However, after implantation with a Vicryl mesh tube using MSC, the lengthening of intestinal regeneration was not recognized.
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| Free Research Field |
消化器外科
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