2017 Fiscal Year Final Research Report
Development of micro/nano-patterned sheet for periodontal tissue regeneration aimed at 3d tissue construction
| Project/Area Number |
25463047
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2018-03-31
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| Keywords | マイクロ・ナノパターン / ナノインプリント / ゼラチン / アパタイト / コンポジットレジン / 歯周組織再生 / 歯根膜線維芽細胞 / 骨芽細胞様細胞 |
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| Outline of Final Research Achievements |
Preparation of micro/nano-patterned sheets was investigated by nanoimprinting with collagen or apatite materials for periodontal tissue regeneration. Micro/nano patterned gelation can be obtained by thermal crosslinking or crosslinking with genipin. The apatite or composite resin patterns were obtained by using appropriate materials and molds. As a result of cell assay, the patterns largely influenced cell adhesion, proliferation, and alignment.
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| Free Research Field |
歯科理工学
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