2015 Fiscal Year Final Research Report
Pathophysiological role of resistin on periodontal disease
| Project/Area Number |
25463253
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SAITO Toshiyuki 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (10170515)
FURUGEN Reiko 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (90253674)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | レジスチン / 相互作用 / 歯周病 |
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| Outline of Final Research Achievements |
Previous studies have reported that human resistin is associated with periodontal disease and released from neutrophils stimulated by periodontal pathogens. The purpose of this study is to examine the pathophysiological role of resistin on periodontal disease. The results in this study showed recombinant human resistin do not significantly change genes and proteins in human periodontal cells and any specific receptors in human periodontal cells was not identified to interact with human resistin. Further study will be needed to clarify a role of resistin on periodontal disease.
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| Free Research Field |
口腔保健学
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