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2015 Fiscal Year Final Research Report

Analysis of the "epicenter of fluctuation" of proteins using mass spectrometry and the cavity omics analysis

Research Project

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Project/Area Number 25513005
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field オミクス計測科学
Research InstitutionHiroshima University

Principal Investigator

Izumi Shunsuke  広島大学, 理学(系)研究科(研究院), 教授 (90203116)

Co-Investigator(Kenkyū-buntansha) Hiraoka Yasuaki  東北大学, 原子分子材料科学高等研究機構, 准教授 (10432709)
Project Period (FY) 2013-04-01 – 2016-03-31
Keywords質量分析 / タンパク質 / パーシステントホモロジー群 / HD交換速度 / トポロジカル・キャビティ
Outline of Final Research Achievements

Speed of the fluctuation of the protein is measured in such as hydrogen deuterium (HD) exchange rate. In the present study, the HD exchange rate that tied the cavity of the protein (cavity), heading the relationship between the common structure of the speed and protein fluctuations, discussed the features of the HD exchange method in protein.

Free Research Field

タンパク質の質量分析を用いた構造解析

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Published: 2017-05-10  

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