When do we have a chance to become a night owl?

2014 Fiscal Year Final Research Report

• Project/Area Number: 25560427
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Basic / Social brain science
• Research Institution: The Institute of Physical and Chemical Research
• Principal Investigator: NIWA Yasutaka 独立行政法人理化学研究所, 生命システム研究センター, 基礎科学特別研究員 (40590071)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: 睡眠覚醒 / Tetシステム

Outline of Final Research Achievements

Starting to examine the detail about night-owl behavior of mutant mice, I realized that it is difficult to determine the condition of Dox administration by using those mice. This is because not all the mutant mice show night-owl behavior and LD to DD light conditioning is required to examine it. So I used different mutant mice which would be controllable by Dox administration and do show less weight and less sleep phenotypes. During this research period, I succeeded in inducing and reversing those phenotypes by just Dox administration via food. Based on the condition of those results, in the future, I will analyze night-owl behavior and determine when the behavior is determined to be repressed.

Free Research Field

複合領域