2014 Fiscal Year Annual Research Report
ナノキャビティの表面プラズモン閉じ込め効果を用いた疾病センサーの開発
| Project/Area Number |
25630019
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| Research Institution | The University of Tokyo |
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Principal Investigator |
J・J Delaunay 東京大学, 工学(系)研究科(研究院), 准教授 (80376516)
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| Co-Investigator(Kenkyū-buntansha) |
田畑 仁 東京大学, 工学(系)研究科(研究院), 教授 (00263319)
藤川 茂紀 九州大学, カーボンニュートラル・エネルギー国際研究 所, 准教授 (60333332)
前田 悦男 東京大学, 工学(系)研究科(研究院), 助教 (60644599)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | ナノマイクロ加工 / マタマテリアル・表面プラズモン |
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| Outline of Annual Research Achievements |
The project purpose is to demonstrate a small-size and low-cost sensor for biomarkers using confined surface plasmons in nano-cavities.
We clarified the mechanism of light confinement in the nano-cavities and applied this knowledge to the nano-cavity design for biomaterial sensing. The mechanism of light trapping in the nano-cavities was described in Advanced Optical Materials, 2, 522, 2014. We show that light is confined in the nano-cavities by coupling plasmonic modes to scalable cavity modes and, therefore, the resonance of the nano-cavites can be controlled by varying the geometrical parameters of the cavities. This property enables tuning of the nano-cavity resonance wavelength in the near infrared region in which detection of biomaterials is most efficient. We fabricated the designed nanocavities and obtained a good agreement between the simulated and the fabricated nano-cavities. The sensitivity of the proposed U-shaped nano-cavities was quantified in terms of the shift in the resonance wavelength. The change in the wavelength of the resonance reflectance dip of the nano-cavities was first investigated by varying the refractive index of the cavity surrounding. Moreover, the ability of the nano-cavities to detect biomarkers was tested using a protein ligand scheme by observing the change in the resonance wavelength upon the selective attachment of proteins on the cavity surfaces. Finally a design enabling low-cost fabrication of the sensitive cavity structure was proposed, tested and published in Applied Physics Letters, 105, 061112, 2014.
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