New remote-functionalization reagents and their reaction application

2014 Fiscal Year Final Research Report

• Project/Area Number: 25660086
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Bioorganic chemistry
• Research Institution: Hokkaido University
• Principal Investigator: FUKUSHI YUKIHARU 北海道大学, (連合)農学研究科(研究院), 准教授 (60218906)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: キラル誘導体化試薬 / 官能基導入 / 9,10-ethanoanthracene / 立体選択的ラジカル反応 / 遠隔位 / ジアステレマー分離

Outline of Final Research Achievements

A study to create new remote-functionalization reagents has been done, however, isn’t complete yet. A new simple method to synthesize cis-11,12-diamino-9,10-dihydro-9,10-ethanoanthracene was invented in the process. The diamine forms a condensed heterocyclic compound after monoimidation, followed by acylation reaction. On the contrary, monoamides and diamides are produced from the same diamine. Hereafter, these diamides or new amide-esters will be candidates for the new reagents.

Free Research Field

農学