2014 Fiscal Year Final Research Report
Generating tissue-engineered small intestine (TESI) from cultured intestinal stem cells.
| Project/Area Number |
25861202
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Digestive surgery
|
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Keywords | TESI / 人工小腸 / 小腸上皮幹細胞 / 小腸間質系幹細胞 / 培養細胞 |
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| Outline of Final Research Achievements |
The procedure for generating TESI from mature intestinal cells was established in a mouse model. Then, TESI was successfully generated from Lgr5 stem cells with further differentiation into intestinal epithelium after 4 weeks of in vivo implantation.
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| Free Research Field |
外科学一般・消化器外科学
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