2014 Fiscal Year Final Research Report
Elucidation of the mechanism of the cognitive function improvement after carotid endarterectomy using the molecular imaging
| Project/Area Number |
25861288
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Iwate Medical University |
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Principal Investigator |
SAITO HIDEO 岩手医科大学, 医学部, 研究員 (70552727)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Keywords | 慢性脳虚血 / 貧困灌流 / PET / 認知機能 / 18F-FDG / 18F-FRP170 / 糖代謝 / 低酸素組織 |
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| Outline of Final Research Achievements |
PET detects hypoxic but viable tissue present in an acute ischmic area in the human brain. The present study using PET with 18F-FRP170 aimed to determine whether tissue with an abnormally elevated uptake of 18F-FRP170 exists in human chronic cerebral ischemia due to unilateral atherosclerotic major cerebral artery occlusive disease.Tissues with abnormally elevated uptake of 18F-FRP170 exist in human chronic cerebral ischemia characterized by a combination of misery perfusion and moderately reduced oxygen metabolism due to unilateral atherosclerotic major cerebral artery occlusive disease.
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| Free Research Field |
脳循環代謝
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