2015 Fiscal Year Final Research Report
Relationship of sudden sensorineural hearing loss and oxidative stress.
| Project/Area Number |
25861543
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Shinshu University |
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Principal Investigator |
KITOH Ryosuke 信州大学, 学術研究院医学系, 助教 (80419358)
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| Research Collaborator |
NISHIO Shin-ya 信州大学, 学術研究院医学系, 助教 (70467166)
USAMI Shin-ichi 信州大学, 学術研究院医学系, 教授 (10184996)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | 突発性難聴 / 酸化ストレス / 遺伝子 |
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| Outline of Final Research Achievements |
To assess the gene association with sudden sensorineural hearing loss (SSNHL), we analyzed the 192 DNA samples from SSNHL patients registered in the intractable inner ear disease gene bank and performed genotyping of the candidate genes, 39 SNPs from 31 genes. As a result SOD1 rs4998557 could be associated with susceptibility to SSNHL in the Japanese population.
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| Free Research Field |
耳鼻咽喉科学
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