Evaluation of Mirror Biofeedback Rehabilitation after Administration of Botulinum Toxin by fMRI

2014 Fiscal Year Final Research Report

• Project/Area Number: 25861565
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Otorhinolaryngology
• Research Institution: The University of Tokushima
• Principal Investigator: TAKAHASHI MIKA 徳島大学, 大学病院, 診療支援医師 (90569104)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Keywords: ｆMRI / 病的共同運動 / ミラーバイオフィードバック療法 / ボツリヌス毒素

Outline of Final Research Achievements

After administration of botulinum A toxin, patients started mirror biofeedback therapy to treat facial synkinesis which was after effects of the peripheral facial paralysis. I confirmed the cerebral cortex motor area which was activated by closed eyes motion and pouted a mouth in fMRI before and after the treatment. Before treatment, the part activated by both exercise was piled up,but the overlap decreased after treatment, and both parts separated. In addition, it is thought that this therapy shows an effect by cortical reorganaization because curative effect does not have influence at the start time of the treatment of facial synkinesis, though facial synkinesis relieved after the botulinum administration if they do not continue mirror biofeedback therapy,facial synkinesis turn worse again.

Free Research Field

耳鼻咽喉科学