Effect of CaCl2 hydrothermal treatment of ceramics

2015 Fiscal Year Final Research Report

• Project/Area Number: 25861855
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Prosthodontics/ Dental materials science and
• Research Institution: Kyushu University
• Principal Investigator: Miyazaki Mami (坂口真実) 九州大学, 大学病院, 研究員 (80608977)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Keywords: セラミック / 生体親和性 / カルシウム修飾 / 口腔上皮

Outline of Final Research Achievements

We explored the affinity reaction of zirconia as an implant abutment material and soft tissue.
We examined for quantitative estimation of hydroxyl, serum protein and proliferation of epithelial cells on the face of zirconia. In oral study in rats, the implants which abutment was composed of zirconia were placed. We examined the sealing of the epithelium around zirconia.
On the face of zirconia, there are some hydroxyl groups that showed affinity for zirconia. Oral epithelial cells adhered and promoted on the surface of zirconia. There formed healthy biologic width around zirconia abutment. In addition, laminin-5 which a component of hemi-desmosome, was expressed at the interface between epithelium and zirconia. In conclusion, on the surface of zirconia, this study demonstrated that it has an adsorptive property of serum protein and adhere to epithelium by bonding structure including hemi-desmosome junction, and formed the healthy biologic width.

Free Research Field

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