2015 Fiscal Year Final Research Report
Preparation of Folate-appended methylated cyclodextrin polyrotaxanes as novel biomaterials
| Project/Area Number |
25870542
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Physical pharmacy
Applied pharmacology
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| Research Institution | Kumamoto University |
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Principal Investigator |
Higashi Taishi 熊本大学, 大学院生命科学研究部, 助教 (20613409)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Keywords | シクロデキストリン / ポリ擬ロタキサン / ポリロタキサン / ワンポット / 超分子 |
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| Outline of Final Research Achievements |
In this study, we prepared cyclodextrin molecular necklaces through one-pot synthesis. In general, multi-step synthesis is required to prepare the cyclodextrin molecular necklaces. 2, 6-Di-O-methyl cyclodextrins, one of the cyclodextrin derivatives, formed molecular necklaces at high temperature with high yield in one-pot. Currently, we perform the applied research of the molecular necklaces.
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| Free Research Field |
物理系薬学
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