2016 Fiscal Year Final Research Report
Modulatory effects of postnatal experience on rat hippocampal local field potentials
Project/Area Number |
26282222
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Brain biometrics
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Research Institution | Institute of Physical and Chemical Research |
Principal Investigator |
Shinohara Yoshiaki 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 (10425423)
|
Co-Investigator(Kenkyū-buntansha) |
遠藤 整 東海大学, 医学部, 講師 (10550551)
田嶋 敦 金沢大学, 医学系, 教授 (10396864)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Keywords | 海馬 / 脳波 / 脳の左右差 / 生後環境 |
Outline of Final Research Achievements |
Postnatal environmental experience has significant effects on brain development. We reported that rat reared in enriched environment after weaning exbibits greater magnitudes and increased synchronized activities of hippocampal gamma oscillations than rats reared in isolated conditions. We found in longer periods, gamma oscillations and synchrony mature also in isolated rats, but much slower than those reared in enriched environment. Moreover, we found that astrocytic spontaneous calcium oscillations have modulatory effects on hippocampal local field potentials in environment-dependent manner.
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Free Research Field |
神経生理学および神経解剖学
|