2016 Fiscal Year Final Research Report
Assessment of Health Effect Induced by Chemicals Contained in Ambient Dust on Asthma Patients and Development of Its Preventive Method
| Project/Area Number |
26340048
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental impact assessment
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 大気粉塵 / 重金属 / 多環芳香族炭化水素類 / 慢性咳嗽 / 咳 / PM2.5 / IgE / 気管支喘息 |
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| Outline of Final Research Achievements |
The health effect of ambient dust including Asian dust and PM2.5 becomes a social issue. In this study, we showed that heavy metals contained in ambient dust were associated with aggravation of symptoms (itchy eye, cough) of adult chronic cough (bronchial asthma, cough variant asthma, atopic cough) patients. The aggravation of symptoms by heavy metals was stronger in patients whose serum IgE level were low. It was suggested that the effect of heavy metals on symptoms of chronic cough patients is stronger in patients whose allergy symptoms were weak.
Constituent of heavy metals was different between total suspended particulate and PM2.5. Especially, the concentrations of heavy metals contained in total suspended particulate became higher, but the concentrations of some heavy metals contained in PM2.5 were not changed in Asian dust days. When the health effect of particulate matters is considered, it is important to take account of their constituent.
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| Free Research Field |
環境化学
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