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2017 Fiscal Year Final Research Report

Effect of ultrasonic irradiation on bacterial biofilms

Research Project

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Project/Area Number 26350543
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical systems
Research InstitutionJichi Medical University

Principal Investigator

Koibuchi Harumi  自治医科大学, 医学部, 講師 (20382848)

Co-Investigator(Kenkyū-buntansha) 藤井 康友  京都大学, 医学研究科, 教授 (00337338)
Project Period (FY) 2014-04-01 – 2018-03-31
Keywords超音波 / 細菌 / バイオフィルム / 表皮ブドウ球菌 / カテーテル関連血流感染症
Outline of Final Research Achievements

Ultrasonic irradiation (US) can decrease the amount of Staphylococcus epidermidis (S. epidermidis) biofilm when the duration of US irradiation is sufficiently long even if the acoustic intensity is low.
In addition, US irradiation can inhibit the formation of S.epidermidis biofilm. And the inhibitory effect of US irradiation at the early stage can reduced the biofilm formation even if the duration time of US irradiation was short.The inhibitory effect of duplicated irradiation on biofilm effect had nearly twice as high as single irradiation, however, the single irradiation at early stage can also reduce the biofilm formation by 17.9 %.

Free Research Field

超音波、細菌学

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Published: 2019-03-29  

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