Development for evaluation of cognitive function using optical imaging aimed at the contribution to rehabilitation approach on cerebral activation

2016 Fiscal Year Final Research Report

• Project/Area Number: 26350636
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Hamamatsu University School of Medicine (2015-2016); Hamamatsu University (2014)
• Principal Investigator: Oboshi Yumi 浜松医科大学, 光尖端医学教育研究センター, 特任助教 (70613975)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: リハビリテーション / 脳賦活 / 光イメージング / 認知機能

Outline of Final Research Achievements

To evaluate the cognitive decline at the early period in the cognitively healthy elderly, we modified the visual working memory task and measured cerebral blood flow responses during the task-set and task period using near-infrared spectroscopy (NIRS). We found that prefrontal activation was larger during the task execution than during the task-set period. However, with repetition of the task sessions, the activation during task-set period tended to be larger and the task-induced activation to be smaller in the frontal pole area. Furthermore, the activation during the task-set period was significantly correlated with the scores of several neuropsychological tests for prefrontal function. As a result, the temporal characteristics of prefrontal activation might reflect the cognitive function of the elderly people.

Free Research Field

リハビリテーション