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2016 Fiscal Year Final Research Report

Neuronal mechanisms for interval timing in cerebral cortex and basal ganglia

Research Project

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Project/Area Number 26350996
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Brain biometrics
Research InstitutionKindai University

Principal Investigator

INASE Masahiko  近畿大学, 医学部, 教授 (80249961)

Project Period (FY) 2014-04-01 – 2017-03-31
Keywords時間認知 / 前頭連合野 / 運動前野 / 神経細胞活動
Outline of Final Research Achievements

To clarify functional roles of prefrontal and medial premotor cortices in interval timing, neuronal activity was recorded from these areas of a monkey performing a duration classification task. A visual stimulus was presented to the animal from 0.8 to 4.8 sec. Following a delay period, the subject was required to classify the stimulus according to presented duration; long, middle or short. Two types of task-related activity were observed from both areas. First, phasic activity was found with constant peak times after the stimulus onset. This activity might function to filter current stimulus duration with the peak time for classification. Second, phasic activity was observed in the delay period, which changed according to the duration categories of the stimulus. This delay activity might represent temporal classification results of stimulus duration. These results suggest that prefrontal and medial premotor cortices share timing-related activity in duration classification.

Free Research Field

脳科学

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Published: 2018-03-22  

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