Control of histamine-producing bacteria using bacteriophages

2016 Fiscal Year Final Research Report

• Project/Area Number: 26450278
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Aquatic life science
• Research Institution: Hokkaido University
• Principal Investigator: YAMAZAKI Koji 北海道大学, 水産科学研究院, 准教授 (40250500)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: ヒスタミン / ヒスタミン生成菌 / バクテリオファージ / 微生物制御 / ヒスタミン食中毒 / ファージセラピー

Outline of Final Research Achievements

This study was investigated the characterization of newly isolated bacteriophages infected to histamaine-producing Morganella morganii and Photobacterium damselae, and utilization of bacteriophages for control of the pathogens and histamine accumulation. Three strains, FSP1, ΦMV-1 and ΦMV-4, for M.morganii and a strain, Phda1, for P.damselae were successfully isolated from river waters in this study. The viable count of M. morganii and histamine accumulation inhibited on tuna meat by the FSP1 treatment. This result suggests that bacteriophages such as FSP1 and Phda1 could be used as a biocontrol agent against M. morganii and P.damselae for treatment of infectious disease treatment or food decontamination.

Free Research Field

食品微生物学