2016 Fiscal Year Final Research Report
Phytochemical research on Malagasy medicinal plants
| Project/Area Number |
26460122
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Natural medicines
|
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| Research Institution | Hiroshima University |
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Principal Investigator |
|
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| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Keywords | マダガスカル / リーシュマニア / ベクター昆虫 |
|---|
| Outline of Final Research Achievements |
Madagascar is one of the most important area for pharamaceutical research because of richness of attractive endemic species. The successful clinical usage of vinca alkaloids proves the importance of further phytochemical research on Malagasy plants. However, the industrial growth and expansion of infrastructure building make this area in crisis. In this study, we successfully achieved several research outcomes, such as collection of various plant materials and evaluation of bioactivities including anti-tumor, anti-Leishmania and vector insects control activities. Finally, we successfully isolated active principles from one of the material and clearly determined the chemical structures of them. These compounds have a potential to be a seed for further pharmaceutical reserch.
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| Free Research Field |
天然物化学
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